(Source: Actelion Ltd) ALLSCHWIL/BASEL, SWITZERLAND - 17 March 2014 - Actelion Ltd (SIX: ATLN) today announced the results of COMPASS-2, a Phase IV, prospective, randomized, double-blind, placebo-controlled, event-driven study evaluating the effect of bosentan on the time to first morbidity or mortality event in patients with symptomatic pulmonary arterial hypertension (PAH) already treated with sildenafil. COMPASS-2 did not meet the primary endpoint of time to first morbidity or mortality event; bosentan showed a risk reduction of 17% versus placebo (p=0.25). In an exploratory analysis, bosentan on top of sildenafil showed an improvement of 21.8 meters in 6MWD at week 16...
↧