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Actelion announces results of the MAESTRO study with macitentan in patients with pulmonary arterial hypertension ...

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ALLSCHWIL/BASEL, SWITZERLAND - 23 January 2017 - Actelion Ltd (SIX: ATLN) today announced that the MAESTRO study to assess the efficacy, safety and tolerability of macitentan in patients with pulmonary arterial hypertension (PAH) due to Eisenmenger Syndrome did not meet its primary objective. Professor Nazzareno Gali�, Head of the Pulmonary Hypertension Center at the Institute of Cardiology, University of Bologna, and Steering Committee member for the MAESTRO study, commented: "The results of the MAESTRO study are very difficult to interpret. We have seen encouraging positive effects of macitentan in the response of N-terminal pro b-type natriuretic peptide plasma levels and hemodynamic...

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