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Study: Cancer Drug Restores Brain Dopamine, Reduces Toxic Proteins in Parkinson, Dementia (GUMC - Georgetown University Medical Center)

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(Source: GUMC - Georgetown University Medical Center) WASHINGTON (July 11, 2016) - A small phase I study provides molecular evidence that an FDA-approved drug for leukemia significantly increased brain dopamine and reduced toxic proteins linked to disease progression in patients with Parkinson's disease or dementia with Lewy bodies. Dopamine is the brain chemical (neurotransmitter) lost as a result of death of dopamine-producing neurons in these neurodegenerative diseases. Researchers from Georgetown University Medical Center (GUMC), say the findings, described in the Journal of Parkinson's Disease, support improved clinical outcomes observed and first reported at the Society for...

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